Circulating Adrenomedullin in Erythropoietin-Induced Hypertension.
نویسندگان
چکیده
منابع مشابه
Role of increased circulating and renal adrenomedullin in rats with malignant hypertension.
Although it has been reported that the circulating adrenomedullin (AM) level is elevated in hypertension and renal failure, the pathophysiological significance of circulating and intrarenal AM in malignant hypertension remains unknown. We investigated the circulating and intrarenal AM system in rats with malignant hypertension by measuring the plasma level, renal tissue level, and mRNA abundanc...
متن کاملCirculating adrenomedullin is increased after heart transplantation.
OBJECTIVE Adrenomedullin (ADM), secreted by the failing human heart, is a newly discovered potent endogenous vasorelaxing and natriuretic peptide that may play a role in cardiorenal regulation. No data are available on ADM in heart-transplant recipients (Htx) and the aim of this study was to determine the short- and long-term responses of ADM after heart transplantation. METHODS Circulating A...
متن کاملArterial hypertension induced by erythropoietin and erythropoiesis-stimulating agents (ESA).
This review summarizes the evidence for a hypertensinogenic effect of Erythropoietin (Epo) in normal human subjects and predialysis, hemodialysis, and continuous ambulatory peritoneal dialysis (CAPD) patients. The possible mechanisms of Epo-induced hypertension are examined with in vivo animal and in vitro data, as well as pathophysiological human studies in both normal subjects and CKD patient...
متن کاملCirculating levels of erythropoietin and its relation to arterial stiffness in patients with hypertension.
BACKGROUND Emerging experimental and clinical data indicates that erythropoietin (EPO) have significant roles in the cardiovascular system. But the relationship between endogenous EPO levels and arterial stiffness remains unknown. We investigated the EPO levels in relation to arterial stiffness parameters in patients with never treated newly diagnosed hypertension (HT). METHODS We studied 42 ...
متن کاملPulmonary hypertension and erythropoietin.
Numerous uremic patients on hemodialysis have pulmonary hypertension attributable to the presence of arteriovenous fistulas, vascular calcification, and endothelial dysfunction due to alterations in the balance between vasoconstrictive and vasodilatory substances. For these reasons, the effects of recombinant human erythropoietin, a drug widely used in patients on dialysis, on the pulmonary cir...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2000
ISSN: 0916-9636,1348-4214
DOI: 10.1291/hypres.23.427